Djibouti is party to the Registration Convention, the Comprehensive Nuclear-Test-Ban Treaty, and the International Telecommunication Constitution and Convention.

Djibouti is a member of the United Nations Committee on the Peaceful Uses of Outer Space (COPUOS) and the International Telecommunication Union (ITU).In addition, as a member of the African Union, Djibouti adheres to the established space framework by the African Union including key positions like the African Space Policy and African Space Strategy. Additionally, Djibouti is a member of the African Space Agency, an intergovernmental organization dedicated to promoting, advising, and coordinating the development and utilization of space science and technology across Africa.